CANDIDEMIA, A BRIEF BIBLIOGRAPHIC REVIEW

Authors

DOI:

https://doi.org/10.47820/recisatec.v4i2.353

Keywords:

candidemia, candida, resistance, virulence factors, Candida auris

Abstract

Candidemia is considered one of the complications of infections caused by Candida fungi in hospitalized patients, resulting in high mortality and morbidity rates. It is a systemic infectious process originating from species of the Candida genus, recognized as the fourth most prevalent cause of bloodstream infections. Therefore, the aim of this work is to conduct a concise literature review addressing topics such as candidemia, resistance, virulence factors, diagnosis, and treatment. For this purpose, a literature review was conducted with secondary data analysis on candidemia in hospitalized patients. Various repositories were used, such as BVS Brazil, Scielo, Pubmed, LILACS, Elsevier, and Medline, with specific descriptors. Studies in Portuguese, English, and Spanish from 2018 to 2023 were included, covering case studies, clinical studies, and systematic reviews, while works outside this period and criteria were excluded. The literature review highlights the growing concern with candidemia due to its high morbidity and mortality, especially in hospitalized patients. Given the diversity of Candida species and their virulence factors, such as Candida auris, multidisciplinary approaches involving clinical evaluation, laboratory cultures, and molecular techniques are crucial for effective diagnosis and treatment, requiring epidemiological monitoring to guide control and prevention strategies.

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Author Biographies

Jefferson Vinicius da Silva

Ms. Biomédico do Hospital das Clínicas da Universidade Federal de Goiás – HC-UFG/EBSERH.

Fátima Ribeiro Dias

Graduação em Farmácia-Bioquímica pela Universidade Federal de Goiás, especialização em Imunologia pela UFG, mestrado em Imunologia e Genética Aplicadas pela Universidade de Brasília e doutorado em Imunologia pela Universidade de São Paulo. Pós-doutorado na St. Radboud University of Nijmegen, na Holanda e na Universidade Federal de São Paulo. Professora Titular da Universidade Federal de Goiás, no Setor de Imunologia, do Departamento de BiotecnologIa e Ciências (DEBIOTEC), do Instituto de Patologia Tropical e Saúde Pública (IPTSP). Coordenadora do Programa de Pós-Graduação em Medicina Tropical e Saúde Pública (PPGMTSP, conceito 5). Coordenadora do Minter (Mestrado Interinstitucional) - PPGMTSP e Centro Universitário Unirg - Tocantins. Orientadora no Programa de Pós-Graduação em Biologia das Relações Parasito-Hospedeiro (IPTSP-UFG). Vice-coordenadora do programa .

Andre Correa Amaral

Formado em Ciências Biológicas e doutorado em Ciências Genômicas e Biotecnologia pela Universidade Católica de Brasília e pós-doutorado na Universidade de Brasília. Coordena projetos nas áreas de biotecnologia e de nanobiotecnologia. Coordenador do Curso de Biotecnologia da Universidade Federal de Goiás. Professor Associado I de Nanobiotecnologia e Biologia Molecular na Universidade Federal de Goiás. Orientador de Mestrado e Doutorado nos PPG em Biologia da Relação Parasito Hospedeiro e pelo PPG em Genética e Biologia Molecular na Universidade Federal de Goiás. Co-orientador de Mestrado e Doutorado pelo PPG em Microbiologia da Universidade de São Paulo. Membro do Grupo Assessor Especial da Diretoria de Relações Internacionais da CAPES. Membro do Instituto Nacional de Ciência e Tecnologia de Estratégias de Interação Patógeno-Hospedeiro (IPH).

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2024-06-07

How to Cite

da Silva, J. V., Ribeiro Dias, F., & Correa Amaral, A. (2024). CANDIDEMIA, A BRIEF BIBLIOGRAPHIC REVIEW. RECISATEC SCIENTIFIC JOURNAL - ISSN 2763-8405, 4(2), e42353. https://doi.org/10.47820/recisatec.v4i2.353

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