ASTRÓCITOS: DO PROTAGONISMO AOS DÉFICITS

Autores

  • Fabiano de Abreu Rodrigues

DOI:

https://doi.org/10.53612/recisatec.v2i10.195

Palavras-chave:

Sistema Nervoso Central, Células Gliais, Encéfalo

Resumo

O presente artigo busca através da metodologia de revisão bibliográfica reunir, analisar e sintetizar as informações mais recentes sobre as diversas funções desempenhadas pelas células gliais, focando nos astrócitos como primordiais para o bom funcionamento do sistema neural. Verificou-se que os astrócitos possuem as funções de isolar, sustentar e nutrir neurônios, são parte integrante e essencial para o controle homeostático passivo das condições e função sináptica; são importantes reguladores multifuncionais do acoplamento neurometabólico, controlam o fluxo sanguíneo do sistema nervoso central pela liberação e produção de moléculas vasoativas, sendo também mediadores primários no local do fluxo sanguíneo em relação a várias atividades neuronais do sistema nervoso central, realizam a destoxificação, fagocitose, possuem funções imunes e desempenho essencial na formação e manutenção da barreira sangue-cérebro (BSC) e assim, consequentemente, das modulações necessárias em respostas imuno-inflamatórias. As recentes descobertas apontam que a deficiência e o mau-funcionamento de astrócitos estão diretamente relacionados às doenças de Alzheimer, e algumas formas de epilepsia, estando correlacionadas também a problemas de memória.

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Biografia do Autor

Fabiano de Abreu Rodrigues

Logos University international

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Publicado

11/10/2022

Como Citar

Abreu Rodrigues, F. de. (2022). ASTRÓCITOS: DO PROTAGONISMO AOS DÉFICITS. RECISATEC - REVISTA CIENTÍFICA SAÚDE E TECNOLOGIA - ISSN 2763-8405, 2(10), e210195. https://doi.org/10.53612/recisatec.v2i10.195

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